【摘要】

目的 探索一种应用脱细胞异体真皮的“内置生物套”技术，降低阴茎的敏感度，观察其对早泄患者的影响。

方法 通过确定适应症后，选择20例早泄患者。采用冠状沟切口，于白膜浅面分离腔穴，植入脱细胞异体真皮，埋没导引针牵引缝合固定近端，远端与深筋膜缝合固定。术后持续加压包扎。6周后可开始性生活。

结果 所有患者术后恢复顺利，平均随访6个月，未发现血肿、感染等并发症。术前平均射精潜伏期0.67min（0.18~1.1min）；术后阴道内射精潜伏期为2.37min（0.82~8.4min）（p<0.05）。

结论 内置生物套技术通过植入脱细胞异体真皮，在阴茎体的皮肤和海绵体之间形成一道人为的组织屏障。从本项临床研究观察来看，该手术损伤小，术后并发症少，是一项相对安全的外科操作，而且可以显著延长早泄患者的阴道内射精潜伏期时间。

关键词 早泄 脱细胞异体真皮 外科治疗

Abstract  Objective  To explore a novel surgical treatment for primary premature ejaculation with an inner condom technique.

Methods: 20 cases of primary premature ejaculation were selected with established inclusion criteria. The inner condom technique was performed after fully discussion and informed consent. A 2 cm incision was made 1.5 cm proximal to the coronal sulcus, through which a sharp dissection was then carried out under the Buck's fascia. A sheet of acellular dermal matrix was transferred to the subcutaneous pocket and fixed with vicry sutures to form an inner condom. The penis was immobilized with elastic bandage for 7 days and sutures removed after 10 days.

Results: The post-operative recovery was uneventful. No wound problem or complications was

recorded during a mean follow up of 6 months. The mean intravaginal ejaculation latency time was increased from 0.67 min to 2.37 min, which is statistically significant.

Conclusions: The inner condom technique may be a safe and easy surgical treatment for premature ejaculation patients. Further studies are mandatory to verify the efficacy of this new treatment.

Key words  Premature ejaculation, Acellular dermal matrix, Surgical treatment